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David Cosman Selected Research

NK Cell Lectin-Like Receptor Subfamily K

8/2006ULBPs, human ligands of the NKG2D receptor, stimulate tumor immunity with enhancement by IL-15.
8/2004Prevalent expression of the immunostimulatory MHC class I chain-related molecule is counteracted by shedding in prostate cancer.
7/2003Effects of human cytomegalovirus infection on ligands for the activating NKG2D receptor of NK cells: up-regulation of UL16-binding protein (ULBP)1 and ULBP2 is counteracted by the viral UL16 protein.
4/2003Intracellular retention of the MHC class I-related chain B ligand of NKG2D by the human cytomegalovirus UL16 glycoprotein.

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David Cosman Research Topics

Disease

5Neoplasms (Cancer)
08/2006 - 11/2002
4Infections
10/2005 - 04/2003
2Tuberculosis (Tuberculoses)
08/2009 - 10/2005
2Melanoma (Melanoma, Malignant)
01/2006 - 11/2002
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
05/2005 - 11/2002
2Cytomegalovirus Infections (Inclusion Disease)
07/2003 - 03/2003
1Hemochromatosis (Bronze Diabetes)
08/2008
1Human Influenza (Influenza)
03/2007
1Stomach Neoplasms (Stomach Cancer)
01/2006
1Leukemia
05/2005
1Pleural Effusion (Pleural Effusions)
01/2005
1Prostatic Neoplasms (Prostate Cancer)
08/2004
1Bone Resorption
11/2002
1T-Cell Leukemia (Leukemia, T Cell)
11/2002
1Carcinoma (Carcinomatosis)
11/2002
1B-Cell Lymphoma (Lymphoma, B Cell)
11/2002
1Rheumatoid Arthritis
02/2002
1Synovitis
02/2002

Drug/Important Bio-Agent (IBA)

9LigandsIBA
08/2009 - 11/2002
6Proteins (Proteins, Gene)FDA Link
08/2008 - 11/2002
4NK Cell Lectin-Like Receptor Subfamily KIBA
08/2006 - 04/2003
4micaIBA
01/2005 - 11/2002
3Carrier Proteins (Binding Protein)IBA
08/2009 - 10/2005
3MHC class I-related chain AIBA
10/2005 - 04/2003
2Natural Killer Cell ReceptorsIBA
03/2007 - 05/2005
2AntigensIBA
01/2006 - 08/2004
2CytokinesIBA
08/2004 - 02/2002
2Membrane Proteins (Integral Membrane Proteins)IBA
04/2004 - 04/2003
1Interleukin-17 (Interleukin 17)IBA
08/2009
1IronIBA
08/2008
1Poly I-CIBA
03/2007
1Hemagglutinins (Hemagglutinin)IBA
03/2007
1Interleukin-15 (Interleukin 15)IBA
08/2006
1CD226 antigenIBA
10/2005
1Messenger RNA (mRNA)IBA
01/2005
1Histocompatibility Antigens Class IIBA
01/2005
1Biomarkers (Surrogate Marker)IBA
08/2004
1RANK LigandIBA
11/2002
1Receptor Activator of Nuclear Factor-kappa B (TRANCE-R)IBA
11/2002
1Monoclonal AntibodiesIBA
11/2002
1LipidsIBA
02/2002
1Peptide Hydrolases (Proteases)FDA Link
02/2002

Therapy/Procedure

1Immunotherapy
08/2004
1Lung Transplantation
03/2003